朱栋

发布者:花文婷发布时间:2022-10-24浏览次数:10

  

职称:教授,博士生导师     E-mail:   dongzhu@njucm.edu.cn            

主要研究方向:中药功效物质识别,富集,筛选新技术以及中药功效物质活性导向的标靶蛋白生物传感。

 

个人简介

近年来主持国家级、部省级科研项目5项。获江苏省六大人才高峰高层次人才;江苏省高校青蓝工程中青年学术带头人;江苏省“333”工程等人才项目。在Analytical Chemistry, ACS Sensors, Biosensors & Bioelectronics, Chemical Communications, Analytica Chimica Acta.等国际期刊发表SCI论文60篇,其中SCI期刊(IF>10)研究性论文 10篇。申请中国发明专利14项,授权4项。

 

承担的主要科研项目

国家自然科学基金(82274219), 项目名称:基于一体化肝脏类器官SERS/FL技术的中药肝毒性早期预警监测及机制研究:以雷公藤为例 在研2023/1-2026.12

国家自然科学基金 (81573388), 项目名称:量子点介孔复合纳米荧光探针靶向筛选中草药中的抗肿瘤Hsp90抑制剂 结题 2015/1-2019.12

国家自然科学基金 (21205064), 项目名称:基于掺杂型量子点的时间分辨FRET 体系的构建及生物传 结题 2013/1-2015.12

 

代表性论文

1. Xuetong Sun, Wenwen Ji, Bei Zhang, Lijuan Ma, Wenjuan Fu, Wenhui Qian, Xiangying Zhang, Jianting Li, Enze Sheng, Yi Tao*, Dong Zhu*. Theranostic microneedle array patch for integrated glycemia sensing and self-regulated release of insulin. Biomaterials Science. 2022,10, 1209-1216

2. Yi Tao*, Lin Chen, Meiling Pan, Fei Zhu, Dong Zhu*. Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation. ACS Sens. 2021, 6, 9, 3146-3162.

3. Su Li, Yu yin Tang, Lin yu Hu, Wen hui Qian, Li juan Ma, Xue tong Sun, Wen wen Ji, Bei Zhang, Shu ying Han, Yu mei Chi*, Dong Zhu*. Autonomously driving multiplexed hierarchical hybridization chain reaction of a DNA cobweb sensor for monitoring intracellular microRNA. Sensors and Actuators B: Chemical.2021, 344, 130205 DOI: 10.1016/j.snb.2021.130205

4. Yuyin Tang, Su Li, Linyu Hu, Xuetong Sun, Bei Zhang, Wenwen Ji, Lijuan Ma, Wenhui Qian, An Kang*, Dong Zhu* Hybrid Poly(AMPS-CS)-Au Microneedle Arrays to Enrich Metabolites from Skin for Early Disease Diagnosis. Adv Healthc Mater. 2021. e2100764. DOI: 10.1002/adhm.202100764

5. Linyu Hu,Weiyi Sun, Yuying Tang, Su Li, Bei Zhang, Xuetong Sun,Wenwen Ji, Lijuan Ma, Haishan Deng, Shuying Han*, Dong Zhu*. Photothermal effect enhancing graphene quantum dots/semiconducting polymer/nanozyme-mediated cancer catalytic therapy. Carbon. 2021, 176, 148-156.

6. Yingying Tang, Wenhui Qian, Bei Zhang, Wenya Liu, Xuetong Sun, Wenwen Ji, Lijuan Ma, Dong Zhu*. None-Loss Target Release of Biomimetic CaCO3 Nanocomposites for Screening Bioactive Components and Target Proteins. ACS Appl. Bio Mater. 2021, 4, 651-659. DOI: 10.1021/acsabm.0c01197

7. Su Li, Jie Chen, Yu Ying Tang, Lin Yu Hu, Wen Hui Qian, Dong Zhu * and Peng Chen*. Green synthesis of upconversion nanocrystals by adjusting local precursor supersaturation under aqueous conditions. Mater. Adv., 2020,1, 2707-2711

8. Shuying Han, Yilin Song, Jiachun Hu, Rui Liu, Yumei Chi, An Kang, Haishan Deng, Dong Zhu Novel computer-assisted separation prediction strategy for online enrichment-HPLC-FLD in simultaneous monitoring of bisphenols in children’s water bottles. Food Chemistry 339 (2021) 127766

9. Yaochen Xie, Haoxuan Ma, Fang liang He, Jiaqi Chen, Yanlai Ji, Shuying Han* and Dong Zhu*. Preparation of a DNA-Tb-MOF conjugate as a time-resolved probe for the detection of SO2 derivatives through an off–on effect. Analyst, 2020, 145, 47724776.

10. Xiao-Jing Zhang, Lin Yu Hu, Yue Hu, Xiao-Tong Yang, Ying-Ying Tang, Yu Ying Tang, Su Li and Dong Zhu*. Tumor-Penetrating Hierarchically Structured Nanomarker for Imaging-Guided Urinary Monitoring of Cancer. ACS Sens. 2020, 5, 1567-1572




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