王若宁

发布者:花文婷发布时间:2022-09-27浏览次数:5649



职称:教授                              E-mail:ruoningw@njucm.edu.cn         

主要研究方向:1. 仿生型智能靶向系统的设计与应用研究2. 中药高效给药递送系统的设计与研究。重点围绕恶性肿瘤、中枢神经系统疾病等重大疾病的药递送瓶颈,设计智能药物载体,利用中药活性组分特征,实现跨越病灶屏障,定位浓集给药”


 

个人简介

王若宁,博士,教授,硕士研究生导师,共青团5163银河主站线路检测委员会副书记(兼),入选全国中医药青年国医精英,江苏省科协青年科技人才托举工程,江苏省“333高层次人才培养工程及中华中医药学会青年人才托举工程A类)等,获江苏省青年颗粒学奖主持包括国家自然科学基金(面上、青年)、江苏省自然科学基金等10项国家级省级厅局级项目。以第一作者或通讯作者在药学、中药学领域顶级学术期刊ACS Nano, Bioactive Materials, Small (Front cover报道), Biomaterials, Acta Pharmaceutica Sinica B, Journal of Controlled Release(4篇), Chemical Engineering Journal,Journal of Medicinal Chemistry, Theranostics, Nano Research, Journal of Nanobiotechnology等发表多篇高水平论文,其中IF>1012篇,申请并公开国家专利10项,授权7PCT 1

现任世界中医药学会联合会经皮给药专业委员会理事;国际VEBLEO协会会士;中国颗粒学会青年理事;中华中医药学会中药制剂分会、中国药理学与安全性研究分会委员;江苏省青科协生物与医药科学专委会委员;江苏省中医药学会药学专委会青年委员兼职工作秘书;南京药学会药剂与药理专委会委员国家自然科学基金评审专家、江苏省科技评估中心中青年科技评审专家。任《Asian Journal of Pharmaceutical Science》《中草药》中英双刊、《5163银河主站线路检测学报》、《中国药科大学学报》等杂志青年编委。参编江苏省高等学校重点教材《工业药剂学》、《药物制剂工程学》。

指导本科生及研究生多次获得国家级大学生创新创业训练计划江苏省研究生实践创新计划,并多次获得国家奖学金。多次获得江苏省本科生优秀毕业设计(论文)一等奖、二等奖及优秀团队指导教师等荣誉称号。获“挑战杯”全国大学生课外学术科技作品竞赛江苏省一等奖、二等奖,江苏省“互联网+”大学生创新创业大赛二等奖指导教师等荣誉称号。


代表性论文

1. Jiwei Cui, Xue Wang, Jinge Li, Anran Zhu, Yingjiang Du, Wei Zeng, Yumiao Guo, Liuqing Di, Ruoning Wang*. Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy against glioblastoma. ACS Nano, 2023, 17: 1464-1484

2. Ruoning Wang, Xiaohong Wang, Junsong Li, Liuqing Di, Jianping Zhou*, Yang Ding*. Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma. Bioactive Materials, 2022, 13: 286-299

3. Ruoning Wang, Chenshuang Zhang, Junsong Li, Jinyu Huang, Yaw Opoku-Damoah, Bo Sun, Jianping Zhou, Liuqing Di*, Yang Ding*. Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics. Biomaterials. 2019, 221: 119413

4. Ruoning Wang, Yue Han, Bo Sun, Ziqiang Zhao, Yaw Opoku-Damoah, Hao Cheng, Huaqing Zhang, Jianping Zhou*, Yang Ding*. Tumor deep penetrating bioparticulates inspired burst intracelluar drug release for precision chemo-phototherapy. Small, 2018, 14: 1703110 

5. Jiwei Cui, Yuanxin Xu, Haiyan Tu, Huacong Zhao, Honglan Wang, Liuqing Di, Ruoning Wang*. Gather wisdom to overcome barriersWell-designed nano-drug delivery systems for treating gliomas. Acta Pharmaceutica Sinica B, 2022, 12: 1100-1125

6. Ruoning Wang*, Xinru Zhang, Jianyu Huang, Kuanhan Feng, Yingjie Zhang, Jie Wu, Lei Ma, Anran Zhu, Liuqing Di*. Bio-fabricated nanodrugs with chemo-immunotherapy to inhibit glioma proliferation and recurrence. Journal of Controlled Release, 2023, 354: 572-587

7. Ruoning Wang*, Xiaohong Wang, Yuting Zhang, Huacong Zhao, Jiwei Cui, Junsong Li*, Liuqing Di*. Emerging prospects of extracellular vesicles for brain disease theranostics. Journal of Controlled Release, 2022, 341: 844-868

8. Ruoning Wang, Xiaochen Gu, Jianping Zhou*, Lingjia Shen, Lifang Yin, Peiying Hua, Yang Ding*. Green design “bioinspired disassembly-reassembly strategy” applied for improved tumor-targeted anticancer drug delivery. Journal of Controlled Release, 2016, 235: 134-146

9. Yuanxin Xu, Kuanhan Feng, Huacong Zhao, Liuqing Di*, Lei Wang*, Ruoning Wang*. Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment. Theranostics, 2022, 12: 1683-1714

10. Jie Wu‡, Lei Ma‡, Danni Sun‡, Xinru Zhang, Jiwei Cui, Yingjiang Du, Yumiao Guo, Xue Wang, LiuqingDi, Ruoning Wang*. Bioengineering extracellular vesicles as novel nanocarriers towards brain disorders. Nano Research, 2022, 1-25

11. Ruoning Wang, Yujie Yang, Mengmeng Yang, Dandan Yuan, Jinyu Huang, Rui Chen, Honglan Wang, Lihong Hu, Liuqing Di, Junsong Li*. Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions. Journal of Nanobiotechnology, 2020, 18: 116 





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